Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines
نویسندگان
چکیده
منابع مشابه
Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines
OBJECTIVE Skeletal muscle is an important secretory organ, producing and releasing numerous myokines, which may be involved in mediating beneficial health effects of physical activity. More than 100 myokines have been identified by different proteomics approaches, but these techniques may not detect all myokines. We used mRNA sequencing as an untargeted approach to study gene expression of secr...
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Proteins secreted by skeletal muscle, so called myokines, have been shown to affect muscle physiology and additionally exert systemic effects on other tissues and organs. Although recent profiling studies have identified numerous myokines, the amount of overlap from these studies indicates that the secretome of skeletal muscle is still incompletely characterized. One limitation of the models us...
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ژورنال
عنوان ژورنال: Molecular Metabolism
سال: 2017
ISSN: 2212-8778
DOI: 10.1016/j.molmet.2017.01.007